FKBP2 Rekombinanter Antikörper

FKBP2 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241166B9

Kat-Nr. : 84077-6-PBS

Synonyme

FKBP 2, FKBP 13, FK506-binding protein 2, EC:5.2.1.8, 241166B9

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  WB analysis using 84077-6-RR (same clone as 84077-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84077-6-RR (FKBP2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84077-6-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 84077-6-RR (same clone as 84077-6-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 84077-6-RR (FKBP2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84077-6-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 84077-6-RR (same clone as 84077-6-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84077-6-RR (FKBP2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84077-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84077-6-RR

  Biolayer interferometry (BLl) kinetic assays of 84077-6-RR against Human FKBP2 were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

Produktinformation

84077-6-PBS bindet in WB, IHC, Indirect ELISA FKBP2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: FKBP2 fusion protein Ag2255
• Vollständiger Name: FK506 binding protein 2, 13kDa
• Berechnetes Molekulargewicht: 142 aa, 16 kDa
• Beobachtetes Molekulargewicht: 13-16 kDa
• GenBank-Zugangsnummer: BC003384
• Gene symbol: FKBP2
• Gene ID (NCBI): 2286
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FKBP2 is also named as FKBP13 and belongs to the FKBP-type PPIase family. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. FKBP2 has a 21-amino acid signal peptide and appears to be membrane-associated(PMID:1713687). It is localized to the lumen of the endoplasmic reticulum (ER). FKBP12 and FKBP13 are highly similar proteins, of molecular masses 12 kDa and 13 kDa respectively, with approx.43 % amino acid identity. The strong homology between FKBP12 and FKBP13 suggests that they may share similar biological functions, although, apart from rotamase activity, details relating to the function of either protein are scant (PMID:8373365).