FKBP9 Polyklonaler Antikörper

FKBP9 Polyklonal Antikörper für IF, WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18073-1-AP

Synonyme

63 kDa FK506 binding protein, 63 kDa FKBP, FK506 binding protein 9, FKBP 63, FKBP 9, FKBP60, FKBP63, FKBP9, PPIase, PPIase FKBP9, Rotamase

---

Galerie der Validierungsdaten

• 

  WB analysis of NIH/3T3 using 18073-1-AP

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 18073-1-AP (FKBP9 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis of L02 using 18073-1-AP

  L02 cells were subjected to SDS PAGE followed by western blot with 18073-1-AP (FKBP9 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  IF Staining of L02 using 18073-1-AP

  Immunofluorescent analysis of L02 cells using 18073-1-AP (FKBP9 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: NIH/3T3-Zellen, L02-Zellen
• Erfolgreiche Detektion in IF: L02-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000
• Immunfluoreszenz (IF): IF : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

18073-1-AP bindet in WB, IF, ELISA FKBP9 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: FKBP9 fusion protein Ag12715
• Vollständiger Name: FK506 binding protein 9, 63 kDa
• Berechnetes Molekulargewicht: 570 aa, 63 kDa
• Beobachtetes Molekulargewicht: 63 kDa
• GenBank-Zugangsnummer: BC101723
• Gene symbol: FKBP9
• Gene ID (NCBI): 11328
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FKBP9 (FK506-binding protein 9, also referred to as FKBP60 or FKBP63) belongs to a family of immunophilins that are able to bind to FK506, an immunosuppressive drug. Several members of the FKBP family, including FKBP9, FKBP13, FKBP23 and FKBP65, localize to the endoplasmic reticulum (ER) as they contain the ER retention motif H/R/KDEL (PMID:32111229). In addition, the FKBP9 mutation was also reported to be associated with disease-free survival rates in pheochromocytoma or paraganglioma (PMID:28386672).