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FLT3 Polyklonaler Antikörper

FLT3 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30297-1-PBS

Synonyme

CD135, Fetal liver kinase-2, FL cytokine receptor, FLK2, FLK-2

Filter:
  • Western Blot (WB) analysis of various lysates using FLT3 Polyclonal antibody (30297-1-AP)

    WB analysis using 30297-1-AP (same clone as 30297-1-PBS)

    THP-1 cells were subjected to SDS PAGE followed by western blot with 30297-1-AP (FLT3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30297-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of THP-1 cells using FLT3 Polyclonal antibody (30297-1-AP)

    IP experiment of THP-1 using 30297-1-AP (same clone as 30297-1-PBS)

    IP result of anti-FLT3 (IP:30297-1-AP, 4ug; Detection:30297-1-AP 1:500) with THP-1 cells lysate 2720 ug. This data was developed using the same antibody clone with 30297-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30297-1-PBS bindet in WB, IP, Indirect ELISA FLT3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FLT3 fusion protein Ag32898
Vollständiger Name fms-related tyrosine kinase 3
Berechnetes Molekulargewicht112 kDa
Beobachtetes Molekulargewicht130 kDa, 150 kDa
GenBank-ZugangsnummerBC126350
Gene symbol FLT3
Gene ID (NCBI) 2322
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FLT3 (also known as CD135 or FLK2) is a tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation, and survival of hematopoietic progenitor cells and of dendritic cells. FLT3 was originally identified by its expression in hematopoietic stem/progenitor cells (PMID: 7507245). It is important for the normal development of hematopoietic stem/progenitor cells. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.