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FNIP2 Rekombinanter Antikörper

FNIP2 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241638F2

Kat-Nr. : 84371-2-PBS

Synonyme

241638F2, FNIP1 like protein, FNIPL, KIAA1450

Filter:
  • Western Blot (WB) analysis of A549 cells using FNIP2 Recombinant antibody (84371-2-RR)

    WB analysis of A549 using 84371-2-RR (same clone as 84371-2-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 84371-2-RR (FNIP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84371-2-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP01240-1

    Cytometric bead array standard curve of MP01240-1

    Cytometric bead array standard curve of MP01240-1, FNIP2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84371-2-PBS. Detection antibody: 84371-1-PBS. Standard: Ag35014. Range: 0.469-60 ng/mL.

  • Affinity and Kinetic Characterization of 84371-2-RR

    Affinity and Kinetic Characterization of 84371-2-RR

    Biolayer interferometry (BLl) kinetic assays of 84371-2-RR against Human FNIP2 were performed. The affinity constant is 4.85 nM.

Geprüfte Anwendungen

Produktinformation

84371-2-PBS bindet in WB, Cytometric bead array, Indirect ELISA FNIP2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen FNIP2 fusion protein Ag35014
Vollständiger Name folliculin interacting protein 2
Beobachtetes Molekulargewicht125 kda
GenBank-ZugangsnummerBC166693
Gene symbol FNIP2
Gene ID (NCBI) 57600
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Folliculin (FLCN)-interacting proteins 1 and 2 (FNIP1, FNIP2) are homologous binding partners of FLCN, a tumor suppressor for kidney cancer. FNIP2 was found to bind to the C terminus of FLCN and to AMPK, like FNIP1. FNIP2 competes with the activating co-chaperone AHSA1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PMID: 18403135).