FNIP2 Rekombinanter Antikörper

FNIP2 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

241638F2

Kat-Nr. : 84371-2-RR

Synonyme

KIAA1450, FNIPL, FNIP1 like protein, 241638F2

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  WB analysis of A549 using 84371-2-RR

  A549 cells were subjected to SDS PAGE followed by western blot with 84371-2-RR (FNIP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 84371-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84371-2-RR against Human FNIP2 were performed. The affinity constant is 4.85 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: A549-Zellen, HeLa-Zellen, MDA-MB-231-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

84371-2-RR bindet in WB, ELISA FNIP2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: FNIP2 fusion protein Ag35014
• Vollständiger Name: folliculin interacting protein 2
• Beobachtetes Molekulargewicht: 125 kda
• GenBank-Zugangsnummer: BC166693
• Gene symbol: FNIP2
• Gene ID (NCBI): 57600
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Folliculin (FLCN)-interacting proteins 1 and 2 (FNIP1, FNIP2) are homologous binding partners of FLCN, a tumor suppressor for kidney cancer. FNIP2 was found to bind to the C terminus of FLCN and to AMPK, like FNIP1. FNIP2 competes with the activating co-chaperone AHSA1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PMID: 18403135).