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FOXD3 Polyklonaler Antikörper

FOXD3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27878-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of HEK-293 cells using FOXD3 Polyclonal antibody (27878-1-AP)

    WB analysis of HEK-293 using 27878-1-AP (same clone as 27878-1-PBS)

    WB result of FOXD3 antibody (27878-1-AP; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-FOXD3 transfected HEK-293 cells. This data was developed using the same antibody clone with 27878-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HEK-293 cells using FOXD3 Polyclonal antibody (27878-1-AP)

    WB analysis of HEK-293 using 27878-1-AP (same clone as 27878-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 27878-1-AP (FOXD3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27878-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27878-1-PBS bindet in WB, Indirect ELISA FOXD3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FOXD3 fusion protein Ag27260
Vollständiger Name forkhead box D3
Berechnetes Molekulargewicht 48 kDa
Beobachtetes Molekulargewicht57-60 kDa
GenBank-ZugangsnummerNM_012183.2
Gene symbol FOXD3
Gene ID (NCBI) 27022
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FOXD3, also named as HFH2, belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. FOXD3 binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. It also acts as a transcriptional activator. FOXD3 promotes development of neural crest cells from neural tube progenitors. It restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. It required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. FOXD3 has one isoform produced by alternative splicing with the MW of 47 kDa. It can be detected as 57-60 kDa in some literature(PMID: 31940493).