FOXN2 Rekombinanter Antikörper

FOXN2 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

240896C8

Kat-Nr. : 83899-2-PBS

Synonyme

240896C8, forkhead box N2, Forkhead box protein N2, HTLF, Human T-cell leukemia virus enhancer factor

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  WB analysis using 83899-2-RR (same clone as 83899-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83899-2-RR (FOXN2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83899-2-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP00842-3

  Cytometric bead array standard curve of MP00842-3, FOXN2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83899-2-PBS. Detection antibody: 83899-4-PBS. Standard: Ag5126. Range: 1.563-100 ng/mL.

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  Affinity and Kinetic Characterization of 83899-2-RR

  Biolayer interferometry (BLl) kinetic assays of 83899-2-RR against Human FOXN2 were performed. The affinity constant is 2.90 nM.

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Geprüfte Anwendungen

Produktinformation

83899-2-PBS bindet in WB, Cytometric bead array, Indirect ELISA FOXN2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: FOXN2 fusion protein Ag5126
• Vollständiger Name: forkhead box N2
• Berechnetes Molekulargewicht: 47 kDa
• Beobachtetes Molekulargewicht: 55 kDa
• GenBank-Zugangsnummer: BC063305
• Gene symbol: FOXN2
• Gene ID (NCBI): 3344
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Forkhead box N2 (FOXN2), a member of the FOX transcription factor family, has been found to play key roles in various types of human cancers. A recent report has indicated that FOXN2 is downregulated and serves as a tumor suppressor in T-cell leukemia. Moreover, downregulation of FOXN2 is closely associated with adverse prognosis in adult glioblastoma multiforme treated with radiotherapy or chemotherapy. (PMID: 30655703)