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FOXN3 Polyklonaler Antikörper

FOXN3 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25399-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using FOXN3 Polyclonal antibody (25399-1-AP)

    WB analysis using 25399-1-AP (same clone as 25399-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25399-1-AP (FOXN3 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25399-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using FOXN3 Polyclonal antibody (25399-1-AP)

    IF Staining of U2OS using 25399-1-AP (same clone as 25399-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using FOXN3 antibody (25399-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 25399-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25399-1-PBS bindet in WB, IF/ICC, Indirect ELISA FOXN3 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FOXN3 fusion protein Ag21929
Vollständiger Name forkhead box N3
Berechnetes Molekulargewicht 490 aa, 54 kDa
Beobachtetes Molekulargewicht 54 kDa
GenBank-ZugangsnummerBC007506
Gene symbol FOXN3
Gene ID (NCBI) 1112
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

As transcriptional regulators, the FOX protein family regulates the development of tissues, embryos as well as carbohydrate and lipid metabolism. Forkhead box N3 (FOXN3), also known as checkpoint suppressor 1 (CHES1), is initially identified from yeast and belongs to the FOX protein family as it contains a conserved FOX DNA binding domain in its N-terminal(PMID: 36450706). FOXN3 had been dysregulated in many types of malignancies including melanoma, osteosarcoma, hepatocellular carcinoma and breast cancer, and its expression level is strongly associated with progression and prognosis of patients(PMID: 31214487).