FOXQ1 Polyklonaler Antikörper

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• KD/KO Validated

FOXQ1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23718-1-PBS

Synonyme

HNF 3/forkhead like protein 1, HFH-1, HFH1, HFH 1, forkhead box Q1

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  WB analysis of mouse kidney using 23718-1-AP (same clone as 23718-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 23718-1-AP (FOXQ1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23718-1-PBS in a different storage buffer formulation.

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  WB analysis of rat kidney using 23718-1-AP (same clone as 23718-1-PBS)

  rat kidney tissue were subjected to SDS PAGE followed by western blot with 23718-1-AP (FOXQ1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23718-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 23718-1-AP (same clone as 23718-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 23718-1-AP (FOXQ1 antibody) at dilution of 1:800 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23718-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

23718-1-PBS bindet in WB, IHC, Indirect ELISA FOXQ1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: FOXQ1 fusion protein Ag20545
• Vollständiger Name: forkhead box Q1
• Berechnetes Molekulargewicht: 403 aa, 41 kDa
• Beobachtetes Molekulargewicht: 42 kDa
• GenBank-Zugangsnummer: BC053850
• Gene symbol: FOXQ1
• Gene ID (NCBI): 94234
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-affinitätsgereinigt
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Forkhead box Q1 (FOXQ1, also known as HFH1), a member of the FOX gene family, contains the core DNA binding domain, whereas the flanking wings of FOXQ1 contribute to its sequence specificity. FOXQ1 is known to repress the promoter activity of smooth muscle-specific genes, such as telokin and SM22α. FOXQ1 expression is regulated by Hoxa1 in embryonic stem cells. [PMID:15722554, 8139574] As a transcription factor, FOXQ1 represses the promoter activity of smooth muscle-specific genes, such as telokin and SM22α, in A10 vascular muscle cells [PMID:10896677].