FPR2 Polyklonaler Antikörper

FPR2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30989-1-PBS

Synonyme

ALXR, FMLP R I, FMLP R II, FMLP related receptor I, FMLP-related receptor I

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  WB analysis of HEK-293 using 30989-1-AP (same clone as 30989-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 30989-1-AP (FPR2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30989-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 30989-1-AP (same clone as 30989-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30989-1-AP (FPR2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30989-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

30989-1-PBS bindet in WB, IHC, Indirect ELISA FPR2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: FPR2 fusion protein Ag34304
• Vollständiger Name: formyl peptide receptor 2
• Berechnetes Molekulargewicht: 351 aa, 39 kDa
• Beobachtetes Molekulargewicht: 42 kDa
• GenBank-Zugangsnummer: BC029125
• Gene symbol: FPR2
• Gene ID (NCBI): 2358
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The formyl peptide receptors (FPRs) are a group of G protein-coupled chemoattractant receptors that play important roles in host defense and inflammation (PMID: 28335409). In humans, three different isoforms are expressed (FPR1, FPR2, and FPR3). FPR2, also known as FPRL1 or ALX, is expressed by many cell types including monocytes, neutrophils, macrophages, astrocytoma cells, and epithelial cells. FPR2 conveys the biological functions of a variety of ligands, including N-formyl-methionyl peptides, the pro-resolution mediators annexin A1 (AnxA1) and lipoxin A4, as well as the activating and proinflammatory protein serum amyloid A (PMID: 22610094).