FRMD1 Polyklonaler Antikörper

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• KD/KO Validated

FRMD1 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31908-1-AP

Synonyme

FERM domain-containing protein 1

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  WB analysis using 31908-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31908-1-AP (FRMD1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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  WB analysis of K-562 using 31908-1-AP

  WB result of FRMD1 antibody (31908-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-FRMD1 transfected K-562 cells.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maus-Kolongewebe, K-562-Zellen, Maushodengewebe, Maus-Thymusgewebe, Ratten-Thymusgewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

31908-1-AP bindet in WB, ELISA FRMD1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: FRMD1 fusion protein Ag36382
• Vollständiger Name: FERM domain containing 1
• Beobachtetes Molekulargewicht: 70 kDa
• GenBank-Zugangsnummer: BC137144
• Gene symbol: FRMD1
• Gene ID (NCBI): 79981
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The FERM structural domain of FRMD1 (FERM Domain Containing 1) is widely found in cytoskeleton-associated proteins, which are capable of connecting the cytoskeleton to the cell membrane and is involved in signaling. FRMD1 is predicted to be involved in the positive regulation of the Hippo signaling pathway and may play a role in the cytoplasmic side of the cytoskeleton and apical plasma membrane. Although there are fewer studies on the role of FRMD1 in disease, its expression pattern in cancer and lymphoid tissues suggests that it may have important biological functions.