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FRZB Monoklonaler Antikörper

FRZB Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2B4A1

Kat-Nr. : 67081-1-PBS

Synonyme

FIZ, FRE, Frezzled, FRITZ, frizzled related protein, Frizzled related protein 1, FRP, FRP 3, FRZB, FRZB 1, FRZB PEN, FRZB1, FZRB, hFIZ, sFRP 3, SFRP3, SRFP3

Filter:
  • Western Blot (WB) analysis of various lysates using FRZB Monoclonal antibody (67081-1-Ig)

    WB analysis using 67081-1-Ig (same clone as 67081-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67081-1-Ig (FRZB antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67081-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of 4T1 cells using FRZB Monoclonal antibody (67081-1-Ig)

    WB analysis of 4T1 using 67081-1-Ig (same clone as 67081-1-PBS)

    4T1 cells were subjected to SDS PAGE followed by western blot with 67081-1-Ig (FRZB antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67081-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67081-1-PBS bindet in WB, Indirect ELISA FRZB und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen FRZB fusion protein Ag28147
Vollständiger Name frizzled-related protein
Berechnetes Molekulargewicht 325 aa, 36 kDa
Beobachtetes Molekulargewicht 36 kDa
GenBank-ZugangsnummerBC027855
Gene symbol FRZB
Gene ID (NCBI) 2487
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Frzb (also known as sFRP3) is a member of the secreted frizzled related protein (SFRP) family, originally identified as a chondrogenic factor during bone morphogenesis (PMID: 29209231). It was subsequently shown to be a regulator in Wnt signaling, and also have a role in regulating cell growth and differentiation in specific cell types. FRZB was seen to be acting as an oncogene in some cancer, such as metastatic renal cancer.