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FSTL1 Monoklonaler Antikörper

FSTL1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1G5G1

Kat-Nr. : 68528-1-PBS

Synonyme

Follistatin-related protein 1, Follistatin-like protein 1, Follistatin related protein 1, Follistatin like protein 1, follistatin like 1

Filter:
  • Western Blot (WB) analysis of various lysates using FSTL1 Monoclonal antibody (68528-1-Ig)

    WB analysis using 68528-1-Ig (same clone as 68528-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68528-1-Ig (FSTL1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68528-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68528-1-PBS bindet in WB, Indirect ELISA FSTL1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen FSTL1 fusion protein Ag33795
Vollständiger Name follistatin-like 1
Berechnetes Molekulargewicht 308 aa, 35 kDa
Beobachtetes Molekulargewicht50-55 kDa
GenBank-ZugangsnummerBC000055
Gene symbol FSTL1
Gene ID (NCBI) 11167
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Follistatin-like 1 (FSTL1), initially discovered as a TGF-β1-induced gene, encodes a 308 amino acid secreted 45-55 kDa glycoprotein with a follistatin domain and two non-functional calcium-binding motifs. FSTL1 has been reported to be involved in the fate determination and maturation of epithelial cells. Ablation of the FSTL1 gene in the mouse results in several structural developmental defects and neonatal lethality due to respiratory failure, demonstrating its functional importance. FSTL1 has been reported to exhibit both pro- and anti-inflammatory actions, with a specific anti-apoptotic and protective effect in cardiac or renal cell injury. Zwijsen et al. (1994) detected several isoforms of FSTL1 with molecular masses of 40 to 48 kD which differs from the 50- to 55-kD products detected by Tanaka et al. (1998) (OMIM).