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FUT2 Polyklonaler Antikörper

FUT2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20288-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using FUT2 Polyclonal antibody (20288-1-AP)

    WB analysis using 20288-1-AP (same clone as 20288-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20288-1-AP (FUT2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20288-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

20288-1-PBS bindet in WB, Indirect ELISA FUT2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FUT2 fusion protein Ag14047
Vollständiger Name fucosyltransferase 2 (secretor status included)
Berechnetes Molekulargewicht 343 aa, 39 kDa
Beobachtetes Molekulargewicht35-39 kDa
GenBank-ZugangsnummerBC001899
Gene symbol FUT2
Gene ID (NCBI) 2524
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Fucosyltransferase 2 (FUT2) is a key enzyme that catalyzes the transfer of fucose to the terminal galactose of type 1 or type 2 disaccharide via α1,2-linkage. FUT2 gene codes for the alpha(1,2)fucosyltransferase responsible for the synthesis of the H antigen, which is the precursor of the ABO histo-blood group antigens in body fluids and on the intestinal mucosa (PMID: 19487333). FUT2 is highly expressed in lung adenocarcinoma (LUAD) and plays a vital role in the tumorigenesis of LUAD (PMID: 36552800). FUT2 has a calculated molecular mass of ~39 kDa, and the 70kDa band might be the glycosylated form.