FXI Polyklonaler Antikörper

FXI Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24321-1-PBS

Synonyme

F11, Coagulation factor XIa heavy chain, Coagulation factor XIa light chain, EC:3.4.21.27, PTA

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  WB analysis using 24321-1-AP (same clone as 24321-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24321-1-AP (FXI antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24321-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

24321-1-PBS bindet in WB, Indirect ELISA FXI und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: FXI fusion protein Ag18004
• Vollständiger Name: coagulation factor XI
• Berechnetes Molekulargewicht: 625 aa, 70 kDa
• Beobachtetes Molekulargewicht: 70 kDa
• GenBank-Zugangsnummer: BC119014
• Gene symbol: F11
• Gene ID (NCBI): 2160
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Factor XI (FXI) is the zymogen of a blood coagulation protease, factor XIa (FXIa), that contributes to hemostasis by activating factor IX. Factor XI is a precursor of an S1 serine protease found in blood plasma. When activated to FXIa, it plays a crucial role in forming and stabilizing fibrin by triggering the activation of factor IX (PMID: 38545505). FXI has 2 isoforms with the molecular mass of 70 kDa and 64 kDa. Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells.