Fas Ligand/CD178 Rekombinanter Antikörper

Fas Ligand/CD178 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Ratte

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242892G9

Kat-Nr. : 98430-1-PBS

Synonyme

ADAM10-processed FasL form, APL, Apt1Lg1, CD178, CD95 ligand

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  FC experiment of Transfected HEK-293T using 98430-1-RR (same clone as 98430-1-PBS)

  1x10^6 HEK-293T cells or Fas Ligand/TNFSF6 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Rat Fas Ligand/TNFSF6 Rabbit RecAb (98430-1-RR, Clone:242892G9) and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were not fixed. This data was developed using the same antibody clone with 98430-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 98430-1-RR (same clone as 98430-1-PBS)

  1x10^6 HEK-293T cells or Fas Ligand/TNFSF6 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Rat Fas Ligand/TNFSF6 Rabbit RecAb (98430-1-RR, Clone: 242892G9) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were not fixed. This data was developed using the same antibody clone with 98430-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98430-1-PBS bindet in FC Fas Ligand/CD178 und zeigt Reaktivität mit Ratten

• Getestete Reaktivität: Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Fas Ligand/CD178 fusion protein Eg3218
• Vollständiger Name: Fas ligand (TNF superfamily, member 6)
• Berechnetes Molekulargewicht: 31 kDa
• GenBank-Zugangsnummer: NM_012908.1
• Gene symbol: Faslg
• Gene ID (NCBI): 25385
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD178, also known as Fas ligand, is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. It is expressed on NK cells, cytotoxic T lymphocytes and activated CD4+ Th1 cells. CD178 transduces apoptotic signal into cells by binding to FAS/CD95. It is involved as a death factor in the regulation of activation-induced cell death, establishment of immune privilege and tumor cell survival.