Fas Ligand/CD178 Rekombinanter Antikörper

Fas Ligand/CD178 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Ratte

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242892G9

Kat-Nr. : 98430-1-RR

Synonyme

ADAM10-processed FasL form, APL, Apt1Lg1, CD178, CD95 ligand

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  FC experiment of Transfected HEK-293T using 98430-1-RR

  1x10^6 HEK-293T cells or Fas Ligand/TNFSF6 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Rat Fas Ligand/TNFSF6 Rabbit RecAb (98430-1-RR, Clone:242892G9) and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were not fixed.

• 

  FC experiment of Transfected HEK-293T using 98430-1-RR

  1x10^6 HEK-293T cells or Fas Ligand/TNFSF6 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Rat Fas Ligand/TNFSF6 Rabbit RecAb (98430-1-RR, Clone: 242892G9) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Transfected HEK-293T cells

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98430-1-RR bindet in FC Fas Ligand/CD178 und zeigt Reaktivität mit Ratten

• Getestete Reaktivität: Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Fas Ligand/CD178 fusion protein Eg3218
• Vollständiger Name: Fas ligand (TNF superfamily, member 6)
• Berechnetes Molekulargewicht: 31 kDa
• GenBank-Zugangsnummer: NM_012908.1
• Gene symbol: Faslg
• Gene ID (NCBI): 25385
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

CD178, also known as Fas ligand, is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. It is expressed on NK cells, cytotoxic T lymphocytes and activated CD4+ Th1 cells. CD178 transduces apoptotic signal into cells by binding to FAS/CD95. It is involved as a death factor in the regulation of activation-induced cell death, establishment of immune privilege and tumor cell survival.