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FceR1a Rekombinanter Antikörper

FceR1a Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241848D1

Kat-Nr. : 84662-3-PBS

Synonyme

FceRIa, FcERI, Fc-epsilon RI-alpha, FCE1A, Fc epsilon RI alpha

Filter:
  • Western Blot (WB) analysis of various lysates using FceR1a Recombinant antibody (84662-3-RR)

    WB analysis using 84662-3-RR (same clone as 84662-3-PBS)

    Human testis was subjected to SDS PAGE followed by western blot with 84662-3-RR (Fc epsilon RI alpha antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84662-3-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84662-3-PBS bindet in WB, Indirect ELISA FceR1a und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Berechnetes Molekulargewicht30kDa
Beobachtetes Molekulargewicht55-65 kDa
GenBank-ZugangsnummerNM_001387280.1
Gene symbol FceR1a
Gene ID (NCBI) 2205
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex, FceRI, with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316). The calculated molecular weight of FceR1a is 30 kDa, the 55- to 70-kDa bands detected by this antibody are probably caused by heterogeneous glycosylation (PMID: 11344350; 12671054).