FceR1a Rekombinanter Antikörper

FceR1a Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242008G6

Kat-Nr. : 98289-1-PBS

Synonyme

242008G6, Fce1a, FceR1, FcERI, Fcr 5

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  FC experiment of MC/9 using 98289-1-RR (same clone as 98289-1-PBS)

  1x10^6 MC/9 cells were surface stained with 0.25 ug Anti-Mouse Fc-epsilon RI-alpha (FcERI) Rabbit RecAb (98289-1-RR, Clone: 242008G6) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98289-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98289-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98289-1-RR against Mouse FceR1a were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

Produktinformation

98289-1-PBS bindet in FC FceR1a und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: FceR1a fusion protein Eg1740
• Vollständiger Name: Fc receptor, IgE, high affinity I, alpha polypeptide
• Berechnetes Molekulargewicht: 29 kDa
• GenBank-Zugangsnummer: NM_010184.2
• Gene symbol: FceR1a
• Gene ID (NCBI): 14125
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex, FceRI, with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316).