FceR1a Rekombinanter Antikörper

FceR1a Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242008G6

Kat-Nr. : 98289-1-RR

Synonyme

242008G6, Fce1a, FceR1, FcERI, Fcr 5

---

• 

  FC experiment of MC/9 using 98289-1-RR

  1x10^6 MC/9 cells were surface stained with 0.25 ug Anti-Mouse Fc-epsilon RI-alpha (FcERI) Rabbit RecAb (98289-1-RR, Clone: 242008G6) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98289-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98289-1-RR against Mouse FceR1a were performed. The affinity constant is below 1 pM.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: MC/9-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98289-1-RR bindet in FC FceR1a und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: FceR1a fusion protein Eg1740
• Vollständiger Name: Fc receptor, IgE, high affinity I, alpha polypeptide
• Berechnetes Molekulargewicht: 29 kDa
• GenBank-Zugangsnummer: NM_010184.2
• Gene symbol: FceR1a
• Gene ID (NCBI): 14125
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex, FceRI, with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316).