Fibrinogen Alpha Chain Polyklonaler Antikörper

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• KD/KO Validated

Fibrinogen Alpha Chain Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20645-1-PBS

Synonyme

FGA, Fib2, Fibrinopeptide A

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  WB analysis of mouse liver using 20645-1-AP (same clone as 20645-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 20645-1-AP (Fibrinogen alpha chain antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon using 20645-1-AP (same clone as 20645-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 20645-1-AP (same clone as 20645-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 20645-1-AP (same clone as 20645-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 20645-1-AP (same clone as 20645-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 20645-1-AP (same clone as 20645-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 20645-1-AP (same clone as 20645-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

20645-1-PBS bindet in WB, IHC, Indirect ELISA Fibrinogen Alpha Chain und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Fibrinogen Alpha Chain fusion protein Ag9567
• Vollständiger Name: fibrinogen alpha chain
• Berechnetes Molekulargewicht: 866 aa, 95 kDa
• Beobachtetes Molekulargewicht: 60 kDa
• GenBank-Zugangsnummer: BC020764
• Gene symbol: Fibrinogen Alpha Chain
• Gene ID (NCBI): 2243
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGA is the alpha chain of fibrinogen. During conversion of fibrinogen to fibrin, fibrinopeptide A is cleaved from FGA by thrombin.