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Fibrinogen Beta Chain Monoklonaler Antikörper

Fibrinogen Beta Chain Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1F8E4

Kat-Nr. : 66186-1-PBS

Synonyme

FGB, fibrinogen beta chain

Filter:
  • Western Blot (WB) analysis of human heart tissue using Fibrinogen Beta Chain Monoclonal antibody (66186-1-Ig)

    WB analysis of human heart using 66186-1-Ig (same clone as 66186-1-PBS)

    human heart tissue were subjected to SDS PAGE followed by western blot with 66186-1-Ig (Fibrinogen beta chain antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66186-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of fetal human brain tissue using Fibrinogen Beta Chain Monoclonal antibody (66186-1-Ig)

    WB analysis of fetal human brain using 66186-1-Ig (same clone as 66186-1-PBS)

    fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66186-1-Ig (Fibrinogen beta chain antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66186-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66186-1-PBS bindet in WB, Indirect ELISA Fibrinogen Beta Chain und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen Fibrinogen Beta Chain fusion protein Ag10205
Vollständiger Name fibrinogen beta chain
Berechnetes Molekulargewicht 491 aa, 56 kDa
Beobachtetes Molekulargewicht 50 kDa
GenBank-ZugangsnummerBC107766
Gene symbol Fibrinogen Beta Chain
Gene ID (NCBI) 2244
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGB is the beta chain of fibrinogen. During conversion of fibrinogen to fibrin, fibrinopeptide B is cleaved from FGB by thrombin. Mutations in the gene of FGB lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.