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Follistatin Polyklonaler Antikörper

Follistatin Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27350-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using Follistatin Polyclonal antibody (27350-1-AP)

    WB analysis using 27350-1-AP (same clone as 27350-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27350-1-AP (Follistatin antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27350-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using Follistatin Polyclonal antibody (27350-1-AP)

    WB analysis using 27350-1-AP (same clone as 27350-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27350-1-AP (Follistatin antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27350-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using Follistatin Polyclonal antibody (27350-1-AP)

    IF Staining of HeLa using 27350-1-AP (same clone as 27350-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using Follistatin antibody (27350-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27350-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27350-1-PBS bindet in WB, IF/ICC, Indirect ELISA Follistatin und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Follistatin fusion protein Ag26401
Vollständiger Name follistatin
Berechnetes Molekulargewicht 33 aa, 7 kDa
Beobachtetes Molekulargewicht 35 kDa
GenBank-ZugangsnummerBC004107
Gene symbol Follistatin
Gene ID (NCBI) 10468
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Follistatin (FST) is a member of the tissue growth factor β family and is a secreted glycoprotein that antagonizes many members of the family, including activin A, growth differentiation factor11 , and myostatin. It binds activin A with high affinity and whose expression can be induced by activin A and several other pro-inflammatory cytokines. Activin A-follistatin complexes are biologically inactive and bind to cell surface heparan sulphate-containing proteoglycans for internalisation and degradation. It has also been found to play a significant role in the management of skeletal muscle size and mass. It also has important roles in early embryonic development, differentiation of ovarian granulosa cells, liver fibrosis and polycystic ovarian syndrome.