Frizzled 2 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

Frizzled 2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24272-1-PBS

Synonyme

FZD2, Frizzled-2, Fz 2, Fz-2, FzE2

---

• 

  WB analysis using 24272-1-AP (same clone as 24272-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24272-1-AP (Frizzled 2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24272-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse colon using 24272-1-AP (same clone as 24272-1-PBS)

  mouse colon tissue were subjected to SDS PAGE followed by western blot with 24272-1-AP (Frizzled 2 antibody at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24272-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 24272-1-AP (same clone as 24272-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24272-1-AP (Frizzled 2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24272-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat kidney using 24272-1-AP (same clone as 24272-1-PBS)

  rat kidney tissue were subjected to SDS PAGE followed by western blot with 24272-1-AP (Frizzled 2 antibody at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse colon using 24272-1-AP (same clone as 24272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 24272-1-AP (Frizzled 2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse colon using 24272-1-AP (same clone as 24272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 24272-1-AP (Frizzled 2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24272-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

24272-1-PBS bindet in WB, IHC, Indirect ELISA Frizzled 2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Frizzled 2 fusion protein Ag18003
• Vollständiger Name: frizzled homolog 2 (Drosophila)
• Berechnetes Molekulargewicht: 565 aa, 64 kDa
• Beobachtetes Molekulargewicht: 64-70 kDa
• GenBank-Zugangsnummer: BC113402
• Gene symbol: Frizzled 2
• Gene ID (NCBI): 2535
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Frizzled 2(FZD2) also known as FzE2, which belongs to the G-protein coupled receptor Fz/Smo family. FZD2 is an important receptor in the Wnt pathway, which is highly expressed in malignant tumors and helps regulate multiple tumor behaviors. Its expression level is related to prognosis. Moreover, high level of FZD2 had significant correlation with poor prognosis in Breast cancer (BC) patients(PMID: 33832493).