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G6PC2 Polyklonaler Antikörper

G6PC2 Polyklonal Antikörper für IHC, IF-P, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, IF-P, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18074-1-PBS

Synonyme

G6Pase 2, IGRP

Filter:
  • Immunoprecipitation (IP) experiment of mouse pancreas tissue using G6PC2 Polyclonal antibody (18074-1-AP)

    IP experiment of mouse pancreas using 18074-1-AP (same clone as 18074-1-PBS)

    IP result of anti-G6PC2 (IP:18074-1-AP, 4ug; Detection:18074-1-AP 1:500) with mouse pancreas tissue lysate 2480 ug. This data was developed using the same antibody clone with 18074-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse pancreas tissue using G6PC2 Polyclonal antibody (18074-1-AP)

    IHC staining of mouse pancreas using 18074-1-AP (same clone as 18074-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 18074-1-AP (G6PC2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18074-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse pancreas tissue using G6PC2 Polyclonal antibody (18074-1-AP)

    IHC staining of mouse pancreas using 18074-1-AP (same clone as 18074-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 18074-1-AP (G6PC2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18074-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse pancreas tissue using G6PC2 Polyclonal antibody (18074-1-AP)

    IF Staining of mouse pancreas using 18074-1-AP (same clone as 18074-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse pancreas tissue using G6PC2 antibody (18074-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18074-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

18074-1-PBS bindet in IHC, IF-P, IP, Indirect ELISA G6PC2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen G6PC2 fusion protein Ag12764
Vollständiger Name glucose-6-phosphatase, catalytic, 2
Berechnetes Molekulargewicht 355 aa, 41 kDa
Beobachtetes Molekulargewicht38-40 kDa
GenBank-ZugangsnummerBC104778
Gene symbol G6PC2
Gene ID (NCBI) 57818
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

G6PC2, also known as IGRP, is a member of the glucose-6-phosphatase catalytic subunit (G6PC) gene family. G6PC2 catalyzes the hydrolysis of glucose-6-phosphate to glucose and inorganic phosphate within the lumen of the endoplasmic reticulum. G6PC2 is mainly expressed in pancreatic islet β-cells. G6PC2 acts to oppose the action of the beta cell glucose sensor, glucokinase, by creating a futile substrate cycle. (PMID: 37855366, PMID: 32569842, PMID: 37552875)