GABARAPL2 Polyklonaler Antikörper
GABARAPL2 Polyklonal Antikörper für ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 10704-1-AP
Synonyme
Geprüfte Anwendungen
Veröffentlichte Anwendungen
| WB | See 1 publications below |
Produktinformation
10704-1-AP bindet in WB, ELISA GABARAPL2 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| In Publikationen genannte Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | GABARAPL2 fusion protein Ag1155 |
| Vollständiger Name | GABA(A) receptor-associated protein-like 2 |
| Berechnetes Molekulargewicht | 14 kDa |
| GenBank-Zugangsnummer | BC005985 |
| Gene symbol | GABARAPL2 |
| Gene ID (NCBI) | 11345 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol |
| Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
GABARAPL2 (also known as Golgi-associated ATPase enhancer of 16 kDa; GATE-16) was originally characterized as a factor essential for intra-Golgi protein transport. Later GABARAPL2 along with LC3 and GABARAP, were identified as the homologs of yeast ATG8 which is a unique ubiquitin-like protein essential for autophagy. When induced GABARAPL2 is first digested by ATG4 family enzymes to become its mature form: GABARAPL2-I, later conjugated to PE lipid as lipidated form: GABARAPL2-II. The lipidated form migrates faster than its mature form on SDS-PAGE gel. GABARAPL2 is strongly expressed in the brain. This antibody, generated against the full-length of GABARAPL2, is specific to GABARAPL2. It does not recognize recombinant GABARAP as well as GABARAPL1.
