GABRA4 Polyklonaler Antikörper

GABRA4 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12979-1-PBS

Synonyme

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  WB analysis of mouse skeletal muscle using 12979-1-AP (same clone as 12979-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 12979-1-AP (GABRA4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12979-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 12979-1-AP (same clone as 12979-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12979-1-AP (GABRA4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12979-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human kidney using 12979-1-AP (same clone as 12979-1-PBS)

  human kidney tissue were subjected to SDS PAGE followed by western blot with 12979-1-AP (GABRA4 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12979-1-PBS in a different storage buffer formulation.

• 

  IP experiment of mouse skeletal muscle using 12979-1-AP (same clone as 12979-1-PBS)

  IP result of anti-GABRA4 (IP:12979-1-AP, 4ug; Detection:12979-1-AP 1:500) with mouse skeletal muscle tissue lysate 2200ug. This data was developed using the same antibody clone with 12979-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

12979-1-PBS bindet in WB, IP, Indirect ELISA GABRA4 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: GABRA4 fusion protein Ag3600
• Vollständiger Name: gamma-aminobutyric acid (GABA) A receptor, alpha 4
• Berechnetes Molekulargewicht: 554 aa, 62 kDa
• Beobachtetes Molekulargewicht: 62-70 kDa
• GenBank-Zugangsnummer: BC035055
• Gene symbol: GABRA4
• Gene ID (NCBI): 2557
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABRA4, encoding the extrasynaptically located α4‐subunit of the GABAA receptor, is involved in the etiology of autism. (PMID: 32028044, 32033586)