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GABRA6 Polyklonaler Antikörper

GABRA6 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21766-1-PBS

Synonyme

Filter:
  • Immunohistochemistry (IHC) staining of mouse cerebellum tissue using GABRA6 Polyclonal antibody (21766-1-AP)

    IHC staining of mouse cerebellum using 21766-1-AP (same clone as 21766-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 21766-1-AP (GABRA6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21766-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse cerebellum tissue using GABRA6 Polyclonal antibody (21766-1-AP)

    IHC staining of mouse cerebellum using 21766-1-AP (same clone as 21766-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 21766-1-AP (GABRA6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21766-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

21766-1-PBS bindet in IHC, Indirect ELISA GABRA6 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen GABRA6 fusion protein Ag16375
Vollständiger Name gamma-aminobutyric acid (GABA) A receptor, alpha 6
Berechnetes Molekulargewicht 453 aa, 51 kDa
GenBank-ZugangsnummerBC096241
Gene symbol GABRA6
Gene ID (NCBI) 2559
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABAA receptors, which are ligand-gated chloride channels. GABAA receptors are formed by pentameric assembly of 19 different subunit subtypes (α1-α6, β1-β3, γ1-γ3, δ, ɛ, π, θ and ρ1-ρ3) (PMID: 21930603). The mutation R46W of GABRA6 is associated with the pathogenesis of childhood absence epilepsy (CAE) (PMID: 21930603).