GABRG2 Monoklonaler Antikörper
GABRG2 Monoklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
human, Kaninchen, Maus, Ratte
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
1H10E1
Kat-Nr. : 68595-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
68595-1-PBS bindet in WB, Indirect ELISA GABRG2 und zeigt Reaktivität mit human, Kaninchen, Maus, Ratten
| Getestete Reaktivität | human, Kaninchen, Maus, Ratte |
| Wirt / Isotyp | Maus / IgG2a |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | GABRG2 fusion protein Ag5489 |
| Vollständiger Name | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
| Berechnetes Molekulargewicht | 467 aa, 54 kDa |
| Beobachtetes Molekulargewicht | 40-54 kDa |
| GenBank-Zugangsnummer | BC059389 |
| Gene symbol | GABRG2 |
| Gene ID (NCBI) | 2566 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
GABRG2 (gamma-aminobutyric acid type A receptor subunit gamma2), which is expected to be located in cell membrane and expressed in brain and retina. The calculated molecular weight of the protein is 54 kDa. This antibody can recognize the 43 kDa band of target (PMID:12091434). And it also has glycosylation modification. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures.

