GABRR1 Polyklonaler Antikörper

GABRR1 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IF, ELISA

Konjugation

Unkonjugiert

Publikationen

2

Kat-Nr. : 25899-1-AP

Synonyme

GABA(A) receptor subunit rho 1, GABA(C) receptor, GABRR1

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Galerie der Validierungsdaten

• 

  WB analysis of mouse brain using 25899-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 25899-1-AP (GABRR1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse skeletal muscle using 25899-1-AP

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 25899-1-AP (GABRR1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maushirngewebe, Maus-Skelettmuskelgewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below
• IF: See 1 publications below

Produktinformation

25899-1-AP bindet in WB, IF, ELISA GABRR1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: GABRR1 fusion protein Ag23165
• Vollständiger Name: gamma-aminobutyric acid (GABA) receptor, rho 1
• Berechnetes Molekulargewicht: 479 aa, 56 kDa
• Beobachtetes Molekulargewicht: 50-56 kDa
• GenBank-Zugangsnummer: BC130344
• Gene symbol: GABRR1
• Gene ID (NCBI): 2569
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GABRR1 is a member of a family of ligand-gated chloride channels that are the major inhibitory neurotransmitter receptors in the central nervous system. GABRR1 acts as a rho-1 receptor of GABA, the major inhibitory neurotransmitter in the vertebrate brain, may play a role in retinal neurotransmission. And then, GABRR1 is highly expressed in the retina and in a lesser extent in brain, lung and thymus. There are 3 isoforms for GABRR1 produced by alternative splicing, with the molecular weights of 46 kDa, 53 kDa, 56 kDa, respectively.

Publikationen

Species	Application	Title
	IF	Insect Sci; Rho 1 participates in parasitoid wasp eggs maturation and host cellular immunity inhibition; Authors - Ruijuan Wang
mouse	WB	Transl Psychiatry; Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice; Authors - Kyosuke Yamanishi