GAD65 Rekombinanter Antikörper

GAD65 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250044B5

Kat-Nr. : 85750-1-PBS

Synonyme

GAD2, EC:4.1.1.15, GAD 65, GAD-65



Geprüfte Anwendungen

Produktinformation

85750-1-PBS bindet in WB, Indirect ELISA GAD65 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Berechnetes Molekulargewicht 65 kDa
Beobachtetes Molekulargewicht65 kDa
GenBank-ZugangsnummerNM_000818
Gene symbol GAD65
Gene ID (NCBI) 2572
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GAD2, also named as GAD65, belongs to the group II decarboxylase family. GAD2 catalyzes the production of GABA. It is responsible for the synthesis of the essential neurotransmitter gamma-aminobutyric acid (GABA) from L-glutamic acid. GAD2 is expressed in nervous and endocrine systems and are thought to be involved in synaptic transmission and INS secretion. Autoantibodies against GAD2 may serve as markers for type I diabetes. Many individuals suffering from an adult onset disorder known as Stiff Person Syndrome (SPS) also express autoantibodies to GAD2. The antibody is specific to GAD2.