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GATM Monoklonaler Antikörper

GATM Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1D12G5

Kat-Nr. : 68513-1-PBS

Synonyme

Transamidinase, L-arginine:glycine amidinotransferase, EC:2.1.4.1, AGAT, 1D12G5

Filter:
  • Western Blot (WB) analysis of pig kidney tissue using GATM Monoclonal antibody (68513-1-Ig)

    WB analysis of pig kidney using 68513-1-Ig (same clone as 68513-1-PBS)

    pig kidney tissue were subjected to SDS PAGE followed by western blot with 68513-1-Ig (GATM antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68513-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using GATM Monoclonal antibody (68513-1-Ig)

    WB analysis using 68513-1-Ig (same clone as 68513-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68513-1-Ig (GATM antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68513-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68513-1-PBS bindet in WB, Indirect ELISA GATM und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen GATM fusion protein Ag3754
Vollständiger Name glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Berechnetes Molekulargewicht 423 aa, 48 kDa
Beobachtetes Molekulargewicht48 kDa
GenBank-ZugangsnummerBC004141
Gene symbol GATM
Gene ID (NCBI) 2628
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GATM, also known as AGAT, produces ornithine and guanidinoacetate (GAA) from arginine and glycine, and is a key enzyme for creatine synthesis. GATM deficiency in early infancy causes neurodevelopmental delay. GATM is predominantly expressed in kidney and pancreas in adults. Decrease of GAMT proteins was observed in proximal tubule damage cases, which links GATM as a general marker for proximal tubule damage. Alternative splicing of GATM generates three isoforms with molecular weights between 44 kDa to 48 kDa.