• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

GBP2 Monoklonaler Antikörper

GBP2 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2D7G4

Kat-Nr. : 68559-1-PBS

Synonyme

2D7G4, EC:3.6.5.-, GBP 2, GBP-2, GTP-binding protein 2

Filter:
  • Western Blot (WB) analysis of various lysates using GBP2 Monoclonal antibody (68559-1-Ig)

    WB analysis using 68559-1-Ig (same clone as 68559-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68559-1-Ig (GBP2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68559-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68559-1-PBS bindet in WB, Indirect ELISA GBP2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen GBP2 fusion protein Ag24108
Vollständiger Name guanylate binding protein 2, interferon-inducible
Berechnetes Molekulargewicht 591 aa, 67 kDa
Beobachtetes Molekulargewicht 67 kDa
GenBank-ZugangsnummerBC022272
Gene symbol GBP2
Gene ID (NCBI) 2634
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GBP2 is a member of the GTPase family and is crucial to host immunity against pathogens. GBP2 is also used as a marker of interferon (IFN) responsiveness, because it is one of the most highly expressed genes after IFN-γ stimulation. Increased GBP2 expression is also associated with a better prognosis in breast cancer and may have a role in T-cell defense against breast cancer. Interestingly, GBP2 expression in NIH/3T3 fibroblasts inhibited Rac activation and matrix metalloproteinase-9 expression, suggesting a possible role for GBP2 in regulating cancer metastasis. The molecular weight of GBP2 is 67 kDa. (PMID: 29072687, 35383115)