GDAP1L1 Monoklonaler Antikörper
GDAP1L1 Monoklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Maus / IgG2b
Getestete Reaktivität
Hausschwein, human, Kaninchen, Maus, Ratte
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
1C7A3
Kat-Nr. : 68340-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
68340-1-PBS bindet in WB, Indirect ELISA GDAP1L1 und zeigt Reaktivität mit Hausschwein, human, Kaninchen, Maus, Ratten
Getestete Reaktivität | Hausschwein, human, Kaninchen, Maus, Ratte |
Wirt / Isotyp | Maus / IgG2b |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | GDAP1L1 fusion protein Ag27717 |
Vollständiger Name | ganglioside-induced differentiation-associated protein 1-like 1 |
Berechnetes Molekulargewicht | 367 aa, 42 kDa |
Beobachtetes Molekulargewicht | 38-40 kDa |
GenBank-Zugangsnummer | BC009014 |
Gene symbol | GDAP1L1 |
Gene ID (NCBI) | 78997 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1L1) belongs to GST superfamily. Owing to its central role in mitochondrial fission, GDAP1L1 is a homologue of GDAP1 implicated in cellular processes, such as cell death, autophagy, aging, and immune response regulation (PMID:32230997). GDAP1L1, a fission factor controlling mitochondrial fission, induces fission upon translocation from the cytosol to mitochondria in response to stress condition (PMID:34638757). Furthermore, the activity of GDAP1L1 is dependent on Drp1. GDAP1, a paralog of GDAP1L1, evokes mitochondrial fragmentation only in the presence of Drp1 in HeLa cells (PMID:19782751).