GDNF Rekombinanter Antikörper

GDNF Rekombinant Antikörper für IHC, IF/ICC, IF-P, FC (Intra), Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, IF/ICC, IF-P, FC (Intra), Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

230358A10

Kat-Nr. : 83087-1-PBS

Synonyme

230358A10, Astrocyte-derived trophic factor, ATF, ATF1, ATF2



Geprüfte Anwendungen

Produktinformation

83087-1-PBS bindet in IHC, IF/ICC, IF-P, FC (Intra), Indirect ELISA GDNF und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen GDNF fusion protein Ag24068
Vollständiger Name glial cell derived neurotrophic factor
Berechnetes Molekulargewicht 211 aa, 24 kDa
Beobachtetes Molekulargewicht 32-40 kDa
GenBank-ZugangsnummerBC069369
Gene symbol GDNF
Gene ID (NCBI) 2668
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Glial-derived neurotrophic factor (GDNF) is a member of the transforming growth factor (TGF)-α family and exhibits potent neuroprotective activity. GDNF is a potent promoter of neuronal survival in the CNS and peripheral nervous system (PNS). It has a relatively high speciicity for dopaminergic neurons and thus become an efective treatment for Parkinson's diseases (PD), with clinical trials currently in progress. Protein dimers of GDNF have a reported molecular weight of 32-40 kDa(PMID: 17982417, PMID: 23251488, PMID: 11429269).