GDNF Rekombinanter Antikörper
GDNF Rekombinant Antikörper für IHC, IF/ICC, IF-P, FC (Intra), Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus
Anwendung
IHC, IF/ICC, IF-P, FC (Intra), Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
230358A10
Kat-Nr. : 83087-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
83087-1-PBS bindet in IHC, IF/ICC, IF-P, FC (Intra), Indirect ELISA GDNF und zeigt Reaktivität mit human, Maus
Getestete Reaktivität | human, Maus |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | GDNF fusion protein Ag24068 |
Vollständiger Name | glial cell derived neurotrophic factor |
Berechnetes Molekulargewicht | 211 aa, 24 kDa |
Beobachtetes Molekulargewicht | 32-40 kDa |
GenBank-Zugangsnummer | BC069369 |
Gene symbol | GDNF |
Gene ID (NCBI) | 2668 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Glial-derived neurotrophic factor (GDNF) is a member of the transforming growth factor (TGF)-α family and exhibits potent neuroprotective activity. GDNF is a potent promoter of neuronal survival in the CNS and peripheral nervous system (PNS). It has a relatively high speciicity for dopaminergic neurons and thus become an efective treatment for Parkinson's diseases (PD), with clinical trials currently in progress. Protein dimers of GDNF have a reported molecular weight of 32-40 kDa(PMID: 17982417, PMID: 23251488, PMID: 11429269).