GFRA2 Polyklonaler Antikörper

GFRA2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55038-1-PBS

Synonyme

GDNF family receptor alpha 2, GDNF family receptor alpha-2, GDNF receptor alpha 2, GDNF receptor alpha-2, GDNF receptor beta

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  WB analysis of human placenta using 55038-1-AP (same clone as 55038-1-PBS)

  human placenta tissue were subjected to SDS PAGE followed by western blot with 55038-1-AP (GFRA2 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55038-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 55038-1-AP (same clone as 55038-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 55038-1-AP (GFRA2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55038-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 55038-1-AP (same clone as 55038-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 55038-1-AP (GFRA2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55038-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

55038-1-PBS bindet in WB, IHC, Indirect ELISA GFRA2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: GDNF family receptor alpha 2
• Berechnetes Molekulargewicht: 52 kDa
• Beobachtetes Molekulargewicht: 41-45 kDa
• GenBank-Zugangsnummer: NM_001495
• Gene symbol: GFRA2
• Gene ID (NCBI): 2675
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GFRA2, also named as GDNFRB, RETL2 and TRNR2, belongs to the GDNFR family. It is a receptor for neurturin. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It is a potent survival factor for central dopaminergic neurons, motor neurons, and several other populations of neurons in the central and peripheral nervous systems. The GDNF signal is mediated by a complex of the receptor tyrosine kinase RET and a glycosylphosphatidylinositol (GPI)-linked protein, GDNFRA. GFRA2 has three isoforms with MW 34-36 kDa, 39-41 kDa and 50-52 kDa. This antibody is specific to GFRA2.