GGTLC1 Rekombinanter Antikörper

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GGTLC1 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

240297D9

Kat-Nr. : 83392-3-PBS

Synonyme

240297D9, Gamma-glutamyltransferase light chain 1, Gamma-glutamyltransferase-like activity 4, Gamma-glutamyltransferase-like protein 6, GGTL6

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  WB analysis of HepG2 using 83392-3-RR (same clone as 83392-3-PBS)

  WB result of GGTLC1 antibody (83392-3-RR; 1:1200; incubated at room temperature for 1.5 hours) with sh-Control and sh-GGTLC1 transfected HepG2 cells. This data was developed using the same antibody clone with 83392-3-PBS in a different storage buffer formulation.

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  WB analysis using 83392-3-RR (same clone as 83392-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83392-3-RR (GGTLC1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83392-3-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP00433-2

  Cytometric bead array standard curve of MP00433-2, GGTLC1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83392-2-PBS. Detection antibody: 83392-3-PBS. Standard: Ag11592. Range: 0.625-80 ng/mL.

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  Affinity and Kinetic Characterization of 83392-3-RR

  Biolayer interferometry (BLl) kinetic assays of 83392-3-RR against Human GGTLC1 were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

Produktinformation

83392-3-PBS bindet in WB, Cytometric bead array, Indirect ELISA GGTLC1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: GGTLC1 fusion protein Ag11592
• Vollständiger Name: gamma-glutamyltransferase light chain 1
• Berechnetes Molekulargewicht: 225 aa, 24 kDa
• Beobachtetes Molekulargewicht: 20-24 kDa
• GenBank-Zugangsnummer: BC040904
• Gene symbol: GGTLC1
• Gene ID (NCBI): 92086
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Gamma-glutamyltransferase light chain 1 (GGTLC1), initially named GGTL6, then GGTLA4, and later GGTLC1 in 2008, is a member of the gamma-glutamyl transferase (GGT) family. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. Knockdown of GGTLC1 in Endometrial cancer (EC) cells was shown to induce G0/G1 phase arrest and apoptosis, underscoring the significance of GGTLC1 as a key regulator of these cellular processes in EC (PMID: 38841516).