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GIMAP5 Monoklonaler Antikörper

GIMAP5 Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1B6F2

Kat-Nr. : 66943-1-PBS

Synonyme

1B6F2, hIAN5, HIMAP3, IAN 5, IAN4

Filter:
  • Western Blot (WB) analysis of Jurkat cells using GIMAP5 Monoclonal antibody (66943-1-Ig)

    WB analysis of Jurkat using 66943-1-Ig (same clone as 66943-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 66943-1-Ig (GIMAP5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66943-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lymphoma tissue using GIMAP5 Monoclonal antibody (66943-1-Ig)

    IHC staining of human lymphoma using 66943-1-Ig (same clone as 66943-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 66943-1-Ig (GIMAP5 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66943-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lymphoma tissue using GIMAP5 Monoclonal antibody (66943-1-Ig)

    IHC staining of human lymphoma using 66943-1-Ig (same clone as 66943-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 66943-1-Ig (GIMAP5 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66943-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66943-1-PBS bindet in WB, IHC, Indirect ELISA GIMAP5 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen GIMAP5 fusion protein Ag18045
Vollständiger Name GTPase, IMAP family member 5
Berechnetes Molekulargewicht 35 kDa
Beobachtetes Molekulargewicht 30-35 kDa
GenBank-ZugangsnummerBC011732
Gene symbol GIMAP5
Gene ID (NCBI) 55340
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GIMAP5 gene encodes immunity-associated nucleotide 5 protein (IAN5) belonging to GTPase immune-associated protein subfamily. GIMAP5 is widely expressed with high levels in lymph node and spleen. The loss of Gimap5 (GTPase of the 5) gene function is the underlying cause of lymphopenia and autoimmune diabetes in the BioBreeding (BB) rat. Mouse gimap5 is necessary for the survival of peripheral T cells, NK/NKT-cell development, hematopoietic progenitor cell survival and the maintenance of normal liver function. GIMAP5 may regulate T lymphocyte survival by mechanisms that operate upstream of mitochondria.