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GIPC3-Specific Polyklonaler Antikörper

GIPC3-Specific Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25479-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using GIPC3-Specific Polyclonal antibody (25479-1-AP)

    WB analysis using 25479-1-AP (same clone as 25479-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25479-1-AP (GIPC3-Specific antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25479-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25479-1-PBS bindet in WB, Indirect ELISA GIPC3-Specific und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name GIPC PDZ domain containing family, member 3
Berechnetes Molekulargewicht 34 kDa
Beobachtetes Molekulargewicht40 kDa
GenBank-ZugangsnummerNM_133261
Gene symbol GIPC3
Gene ID (NCBI) 126326
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Human PDZ domain-containing protein GIPC3 is a member of the GIPC (GAIP-interacting protein C-terminus) gene family, which is characterized by a single, conserved PDZ domain and GIPC homology (GH1 and GH2) domains. Aberrant expression of GIPC3 has been evidenced to correlate to the audiogenic seizures and sensorineural hearing loss in mouse and human (PMID: 36301034, 21326233). GIPC3 is upregulated in multiple cancer types, with a significant positive correlation of its expression with Hh signaling identified in melanoma cell lines (PMID: 34224745). This antibody is highly specific for GIPC3 protein.