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GLMN Polyklonaler Antikörper

GLMN Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32645-1-PBS

Synonyme

FAP, FAP48, FAP68, FK506-binding protein-associated protein, FKBP-associated protein

Filter:
  • Western Blot (WB) analysis of various lysates using GLMN Polyclonal antibody (32645-1-AP)

    WB analysis using 32645-1-AP (same clone as 32645-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32645-1-AP (GLMN antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32645-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32645-1-PBS bindet in WB, Indirect ELISA GLMN und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen GLMN fusion protein Ag37763
Vollständiger Name glomulin, FKBP associated protein
Berechnetes Molekulargewicht 68 kDa
Beobachtetes Molekulargewicht 68 kDa
GenBank-ZugangsnummerBC001257
Gene symbol GLMN
Gene ID (NCBI) 11146
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Glomulin (GLMN) is a regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes (PMID: 22405651; 22748924). It inhibits E3 ubiquitin ligase activity by binding to RBX1 (via the RING domain) and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34 (PMID: 22405651; 22748924). GLMN is essential for normal vasculature development and contributes to the regulation of RPS6KB1 phosphorylation (PMID: 11845407; 11571281).