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GMDS Rekombinanter Antikörper

GMDS Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251146A1

Kat-Nr. : 86435-1-PBS

Synonyme

EC:4.2.1.47, GDP-D-mannose dehydratase, GDP-mannose 4,6 dehydratase, GMD, SDR3E1

Filter:
  • Western Blot (WB) analysis of various lysates using GMDS Recombinant antibody (86435-1-RR)

    WB analysis using 86435-1-RR (same clone as 86435-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86435-1-RR (GMDS antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86435-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86435-1-PBS bindet in WB, Indirect ELISA GMDS und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen GMDS fusion protein Ag7319
Vollständiger Name GDP-mannose 4,6-dehydratase
Berechnetes Molekulargewicht 42 kDa
Beobachtetes Molekulargewicht42 kDa
GenBank-ZugangsnummerBC000117
Gene symbol GMDS
Gene ID (NCBI) 2762
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GDP-D-mannose-4,6-dehydratase (GMDS) is the key enzyme in the 'de novo' pathway of GDP-L-fucose biosynthesis(PMID:10462046). The enzyme is also named as GMD and belongs to the GDP-mannose 4,6-dehydratase family. The gene encodes a 42 kDa protein that catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor.