GNE Monoklonaler Antikörper

GNE Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2A11E10

Kat-Nr. : 67649-1-PBS

Synonyme

2A11E10, Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, GLCNE, hydrolyzing, IBM2

---

• 

  WB analysis using 67649-1-Ig (same clone as 67649-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67649-1-Ig (GNE antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67649-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

67649-1-PBS bindet in WB, Indirect ELISA GNE und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: GNE fusion protein Ag18702
• Vollständiger Name: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
• Berechnetes Molekulargewicht: 722 aa, 79 kDa
• Beobachtetes Molekulargewicht: 79 kDa
• GenBank-Zugangsnummer: BC121179
• Gene symbol: GNE
• Gene ID (NCBI): 10020
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The bifunctional enzyme UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE) is essential for early embryonic development and catalyzes the rate limiting step in sialic acid biosynthesis. It plays an important role in neuronal cell and brain development, and is strongly involved in cardiac tissue and skeletal muscle early survival and organization.. This protein has 5 isoforms produced by alternative splicing.