GNG13 Polyklonaler Antikörper

GNG13 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18223-1-PBS

Synonyme

h2 35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13, G(gamma)13

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  WB analysis using 18223-1-AP (same clone as 18223-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 18223-1-AP (GNG13 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18223-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

18223-1-PBS bindet in WB, Indirect ELISA GNG13 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: GNG13 fusion protein Ag13007
• Vollständiger Name: guanine nucleotide binding protein (G protein), gamma 13
• Berechnetes Molekulargewicht: 67 aa, 8 kDa
• Beobachtetes Molekulargewicht: 8 kDa
• GenBank-Zugangsnummer: BC093760
• Gene symbol: GNG13
• Gene ID (NCBI): 51764
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GNG13 (Guanine nucleotide-binding protein G (G gamma 13)) is a gene that encodes a gamma subunit of a heterotrimeric G protein. It is expressed in taste, retinal, and neuronal tissues and is crucial for taste transduction. In the main olfactory epithelium (MOE), most olfactory sensory neurons (OSNs) express G proteins consisting of Gαolf and Gβ1γ13. Conditional knockout of the Gng13 gene in mice significantly altered the MOE's gene expression profile and impaired the mutant animals' food - seeking capabilities (PMID: 30157062).