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GNG7 Polyklonaler Antikörper

GNG7 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31393-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using GNG7 Polyclonal antibody (31393-1-AP)

    WB analysis using 31393-1-AP (same clone as 31393-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31393-1-AP (GNG7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31393-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31393-1-PBS bindet in WB, Indirect ELISA GNG7 und zeigt Reaktivität mit Maus, Ratten

Getestete Reaktivität Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen GNG7 fusion protein Ag34754
Vollständiger Name guanine nucleotide binding protein (G protein), gamma 7
Berechnetes Molekulargewicht 8 kDa
Beobachtetes Molekulargewicht10 kDa
GenBank-ZugangsnummerBC014466
Gene symbol GNG7
Gene ID (NCBI) 2788
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GNG7 belongs to the large guanine nucleotide binding protein γ family and is located on chromosome 19. Related genes of the G protein family are involved in various transmembrane signaling transduction pathways. GNG7 may be associated with transmembrane signaling pathways and involved in cell contact-induced growth arrest, thus repressing uncontrolled cell proliferation in multicellular organisms. GNG7 is a heterotrimeric G protein subunit with ubiquitous expression in various tissues but low expression in cancer. GNG7 overexpression inhibited cell growth and tumorigenicity of esophageal carcinoma cells. Also, GNG7 was confirmed as an essential autophagy-inducing agent and participated in inhibiting tumor progression through mTOR pathway (PMID: 30864685, 35281820, 36159963).