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GNRHR Rekombinanter Antikörper

GNRHR Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

7E11

Kat-Nr. : 82847-1-PBS

Synonyme

GnRH R, GnRH receptor, GNRHR, GNRHR1, GRHR, LHRHR, LRHR

Filter:
  • Western Blot (WB) analysis of various lysates using GNRHR Recombinant antibody (82847-1-RR)

    WB analysis using 82847-1-RR (same clone as 82847-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82847-1-RR (GNRHR antibody) at dilution of 1:5100 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82847-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

82847-1-PBS bindet in WB, Indirect ELISA GNRHR und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name GnRH receptor
Berechnetes Molekulargewicht 38 kDa
Beobachtetes Molekulargewicht~38 kDa
GenBank-ZugangsnummerNM_000406
Gene symbol GNRHR
Gene ID (NCBI) 2798
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GNRHR, also named GRHR, belongs to the G-protein coupled receptor 1 family. GNRHR is a receptor for GnRH that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform2 of GNRHR may act as an inhibitor of GnRH-R signaling. Defects in GNRHR are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Defects in GNRHR are a cause of fertile eunuch syndrome. The predicted unmodified molecular weight of the human GNRHR is ~38 kDa, the larger band (50-65 kDa) is likely to represent a glycosylated form of GNRHR.