GPR126 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

GPR126 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17774-1-PBS

Synonyme

---

• 

  IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17774-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17774-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17774-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17774-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse lung using 17774-1-AP (same clone as 17774-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17774-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse lung using 17774-1-AP (same clone as 17774-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17774-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17774-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17774-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

17774-1-PBS bindet in IHC, Indirect ELISA GPR126 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: GPR126 fusion protein Ag12195
• Vollständiger Name: G protein-coupled receptor 126
• Berechnetes Molekulargewicht: 1222 aa, 137 kDa
• GenBank-Zugangsnummer: BC075798
• Gene symbol: GPR126
• Gene ID (NCBI): 57211
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GPR126 (G protein-coupled receptor 126) is a member of the adhesion GPCR family. GPR126 is all widely expressed on stromal cells (PMID: 25713288). It is essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PMID: 24227709). GPR126 regulates neural, cardiac and ear development by G-protein- and/or N-terminus-dependent signaling (PMID: 24082093, PMID: 24067352). GPR126 also stimulates VEGF signaling and angiogenesis by modulating VEGF receptor 2 expression through STAT5 and GATA2 in endothelial cells.