GPR126 Rekombinanter Antikörper

GPR126 Rekombinant Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

6M2

Kat-Nr. : 81632-1-PBS

Synonyme

APG1, DREG, G protein coupled receptor 126, GPR126, PS1TP2, VIGR

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  IHC staining of mouse kidney using 81632-1-RR (same clone as 81632-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 81632-1-RR (GPR126 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81632-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 81632-1-RR (same clone as 81632-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 81632-1-RR (GPR126 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81632-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

81632-1-PBS bindet in IHC, Indirect ELISA GPR126 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: GPR126 fusion protein Ag12195
• Vollständiger Name: G protein-coupled receptor 126
• Berechnetes Molekulargewicht: 1222 aa, 137 kDa
• GenBank-Zugangsnummer: BC075798
• Gene symbol: GPR126
• Gene ID (NCBI): 57211
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GPR126 (G protein-coupled receptor 126) is a member of the adhesion GPCR family. GPR126 is all widely expressed on stromal cells (PMID: 25713288). It is essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PMID: 24227709). GPR126 regulates neural, cardiac and ear development by G-protein- and/or N-terminus-dependent signaling (PMID: 24082093, PMID: 24067352). GPR126 also stimulates VEGF signaling and angiogenesis by modulating VEGF receptor 2 expression through STAT5 and GATA2 in endothelial cells.