GPR137 Polyklonaler Antikörper

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• KD/KO Validated

GPR137 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11929-1-PBS

Synonyme

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  IHC staining of human gliomas using 11929-1-AP (same clone as 11929-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas using 11929-1-AP (GPR137 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

11929-1-PBS bindet in IHC, Indirect ELISA GPR137 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: GPR137 fusion protein Ag2611
• Vollständiger Name: G protein-coupled receptor 137
• Berechnetes Molekulargewicht: 396 aa, 44 kDa
• GenBank-Zugangsnummer: BC033920
• Gene symbol: GPR137
• Gene ID (NCBI): 56834
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

G protein-coupled receptors (GPRs) are highly related to oncogenesis and cancer metastasis. G protein-coupled receptor 137 (GPR137) was initially reported as a novel orphan GPR about 10 years ago. GPR137 is ubiquitously expressed in the central nervous system (CNS), mainly in the hippocampus (PMID: 22025619). GPR137 is involved in the progression of human glioma, suggesting GPR137 as a potential oncogene of glioma cells (PMID: 24870220). Recent study shows that GPR137 plays an important role in colon cancer cell proliferation (PMID: 25301753).