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GPR17 Rekombinanter Antikörper

GPR17 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250471E11

Kat-Nr. : 86089-1-PBS

Synonyme

G protein coupled receptor 17, G-protein coupled receptor 17, P2Y like receptor, P2Y-like receptor, R12

Filter:
  • Western Blot (WB) analysis of various lysates using GPR17 Recombinant antibody (86089-1-RR)

    WB analysis using 86089-1-RR (same clone as 86089-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 86089-1-RR (GPR17 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86089-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86089-1-PBS bindet in WB, Indirect ELISA GPR17 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen GPR17 fusion protein Ag4106
Vollständiger Name G protein-coupled receptor 17
Berechnetes Molekulargewicht 367 aa, 41 kDa
Beobachtetes Molekulargewicht48 kDa
GenBank-ZugangsnummerBC031653
Gene symbol GPR17
Gene ID (NCBI) 2840
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GPR17 is a G protein-coupled receptor (GPCR) that plays a significant role in various physiological processes, particularly in the central nervous system (CNS). GPR17 is considered a modulator of CNS myelination and is involved in reconstructing and repairing demyelinating plaques caused by ongoing inflammatory processes, such as in multiple sclerosis (MS). It is present in nerve cells and precursor oligodendrocyte cells, playing a role in the differentiation and maturation of oligodendrocytes (PMID: 32182666). GPR17 is a multifaceted GPCR with implications in immune regulation, glucose metabolism, neurodegenerative diseases, and potentially in treating anxiety disorders.