GPR179 Polyklonaler Antikörper

GPR179 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29934-1-PBS

Synonyme

GPR158L1, G protein coupled receptor 179

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  WB analysis using 29934-1-AP (same clone as 29934-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 29934-1-AP (GPR179 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29934-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 29934-1-AP (same clone as 29934-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 29934-1-AP (GPR179 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29934-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 29934-1-AP (same clone as 29934-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 29934-1-AP (GPR179 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29934-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

29934-1-PBS bindet in WB, IHC, Indirect ELISA GPR179 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: GPR179 fusion protein Ag32180
• Vollständiger Name: G protein-coupled receptor 179
• Berechnetes Molekulargewicht: 257 kDa
• Beobachtetes Molekulargewicht: 260-270 kDa
• GenBank-Zugangsnummer: NM_001004334.3
• Gene symbol: GPR179
• Gene ID (NCBI): 440435
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GPR179 (Probable G-protein coupled receptor 179) belongs to the glutamate receptor subfamily of GPCRs, which is involved in signal transduction through retinal depolarizing bipolar cells. The protein has an EGF-like calcium binding domain and a seven transmembrane domain in the N-terminal region of the protein. Mutations in this gene are associated with congenital stationary night blindness type 1E. GPR179 is expressed in retinal bipolar cells and upregulated in rd1 mice retina with Pde6b mutations (PubMed: 22325361, PubMed: 22325362).